Sequential Circuits Prophet 5 is an analog synthesizer that was designed and manufactured by Sequential Circuits between 1978 and 1984. With five voices of polyphony, the Prophet-5 is one of the first polyphonic analog synthesizers with patch memory. About 6,000 units were produced in three revisions by Dave Smith and John Bowen. This was later accompanied by the Prophet-10, a version with ten voices of polyphony through an additional circuit board and keyboard.

Sequential Circuits Prophet 5 is known for its use by progressive rock bands and film composers. Due to its success, the Prophet-5 has been emulated in software synthesizers and analog hardware. Through his company Dave Smith Instruments, and later under the Sequential Circuits brand, Smith has developed updated versions of the Prophet-5.

Notable artists and music groups who have used the Prophet-5 or Prophet-10 in their work include:

  • ABBA (Benny Andersson)
  • Dieter Bohlen (of Modern Talking)[3]
  • Doobie Brothers
  • John Carpenter
  • The Cars
  • Vince Clarke
  • Phil Collins
  • Depeche Mode
  • Thomas Dolby
  • Duran Duran
  • Eurythmics
  • Peter Gabriel
  • Genesis – Tony Banks
  • Hall & Oates
  • Human League
  • Iva Davies (of Icehouse)[7]
  • INXS
  • Jean-Michel Jarre
  • Keff McCulloch[8]
  • Journey – Gregg Rolie[9]
  • Kombi (band)
  • Kraftwerk
  • Philip Glass
  • Madonna[10]
  • Mannheim Steamroller
  • New Order
  • No Doubt
  • Gary Numan
  • Berlin
  • Pat Metheny Group (Lyle Mays)
  • Pet Shop Boys
  • Pink Floyd
  • Radiohead
  • Skinny Puppy[11]
  • Squeeze
  • Steely Dan
  • Talking Heads
  • Thompson Twins
  • Weather Report (Josef Zawinul
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